Introduction

For each commonly used drug (listed on right) there is information provided for possible positive effects from use, possible neutral effects from use, possible negative effects from use, overdose amount, class, standard dosage, and notes on dangers and usage. There are also several articles below on a variety of drug education and safety related topics.

BASIC INFO
What is harm reduction?
Drug use vs drug abuse
Terminology and Classifications
What is ego death?

SAFETY DURING USE
What is the safest way to do drugs?
Mental health and drug use
Addiction Prevention
Where can I buy testing kits?
How to use needles safely
Cold water extraction
Drug Interactions

RISK MANAGEMENT
What to do in case of an overdose
Addiction support
Research Chemicals
What is serotonin syndrome?
Drug-Induced Psychosis
Delusions and Paranoia

Alcohol

Possible positive effects from use:
- Anxiety suppression
- Relaxation
- Pain relief
- Physical euphoria

Possible neutral effects from use:
- Amnesia
- Dizziness
- Frequent urination
- Disinhibition
- Increased libido

Possible negative effects from use:
- Nausea
- Dehydration
- Double vision
- Temporary erectile dysfunction

Overdose amount: 15-20 shots

Class: Depressant

Standard dosage: 1-3 shots depending on your physical size and natural tolerance

Notes: Do not mix with acitomentaphin (ibuprofen). If you get alcohol poisoning when using a non oral ROI, a hospital will not be able to pump your stomach and you will be at much higher risk for serious damage or death. It is generally a bad idea to mix alcohol with anything aside from marijuana. It is physically safe to mix alcohol with psychedelics, but it is known to have negative cognitive effects.

Alprazolam (Xanax)

Possible positive effects from use:
- Physical euphoria
- Anxiety suppression
- Seizure suppression

Possible neutral effects from use:
- Energy
- Sedation

Possible negative effects from use:
- Blackouts
- Nausea

Overdose amount: Around 1000 milligrams per kilogram of body weight. Serious danger is unlikely unless mixed with other substances.

Class: Benzodiazepine

Standard dosage: 5-20 milligrams

Notes: Do not mix with depressants or dissociatives as this increases risks.

Ayahuasca

Possible positive effects from use:
- Physical euphoria
- Addiction suppression
- Analysis enhancement
- Creativity enhancement
- Catharsis
- Empathy enhancement
- Personal bias suppression
- Spirituality enhancement

Possible neutral effects from use:
- Stimulation
- Sedation
- Delusions
- Suggestibility enhancement
- Ego death
- Hallucinations
- Internal hallucinations

Possible negative effects from use:
- Motor control loss
- Stomach pain
- Dehydration
- Nausea

Overdose amount: An incredibly unreasonable amount we haven't been able to define yet

Class: Hallucinogen

Standard dosage: Unsure

Notes: This is pretty safe physically. Do not mix with other serotonin enhancing drugs such as cocaine, ecstasy, meth, or nicotine as this can add the risk of serotonin syndrome. Look HERE for information and tips on mental/emotional health when using psychedelics.

Caffeine

Possible positive effects from use:
- Euphoria
- Focus enhancement

Possible neutral effects from use:
- Wakefullness
- Stimulation

Possible negative effects from use:
- Nausea
- Anxiety
- Cognitive fatigue

Overdose amount: 150-200 milligrams

Class: Stimulant

Standard dosage: 26-95 milligrams

Notes: Caffeine is fairly safe (discounting the high addiction potential) unless you take a very high dosage.

Cocaine/crack

Possible positive effects from use:
- Physical euphoria
- Anxiety suppression
- Motivation enhancement

Possible neutral effects from use:
- Stimulation
- Frequent urination
- Tactile hallucinations
- Mouth numbing
- Wakefulness

Possible negative effects from use:
- Irregular heartbeat
- Irritability
- Psychosis
- Dehydration
- Temporary erectile dysfunction
- Cardiovascular damage
- Paranoia

Overdose amount: 30 milligrams to 5 grams depending on tolerance

Class: Stimulant

Standard dosage: 5-30 milligrams

Notes: Do not mix with alcohol. Do not mix with other stimulants, DXM or nicotine as this increases heart strain. Do not mix with depressants as this can cause the delay of overdose symptoms and increase heart strain. Do not mix with ecstasy as this greatly increases neurotoxicity.

Codeine

Possible positive effects from use:
- Pain releif
- Physical euphoria
- Cognitive euphoria
- Anxiety suppression

Possible neutral effects from use:
- Sedation
- Decreased libido
- Sleepiness

Possible negative effects from use:
- Itching
- Consipation
- Difficulty urinating
- Nausea

Overdose amount: 450-800 milligrams

Class: Opioid

Standard dosage: 30-100 milligrams

Notes: At above 400 milligrams effects will no longer increase. Mixing with depressants can cause loss of consciousness, vomiting, and shallow breathing which is just as dangerous as an overdose if you aren't with someone who can get you into recovery position and watch you. Mixing with stimulants can lead to dangerous dehydration levels. Dissociatives can cause the same effects as mixing with depressants with the added effect of delusions and amnesia.